Opioids can worsen depression over time, even when used as prescribed. Learn how mood changes happen, what to watch for, and how to monitor your mental health safely while managing chronic pain.
Opioid tolerance is a normal biological response where your body needs higher doses over time to get the same pain relief. It's not addiction, but it increases overdose risk - especially if you stop and restart. Learn why doses rise, how to stay safe, and what doctors can do.